Tributyrin
A source of butyrate
In plain language
Three butyrate units linked to one glycerol backbone. A fat that releases butyrate as it is digested.
CoreBiome® is the branded tributyrin selected for development.
Tributyrin, explainedOpen Origin · Formula 01
Know what
goes in.
Formula 01 is a two-ingredient capsule in development for the digestive system: tributyrin, a source of butyrate, and zinc L-carnosine.
Every active printed by amount. Every lot tested, results public. Evidence kept in context. Targeting late 2026.
Explore Formula 01
Formula 01CoreBiome® + PepZinGI®
Where development standsManufacturer qualification and prototypes
TargetLate 2026, Amazon US first
Why this exists
A supplement label
should answer questions.
Most don’t. Proprietary blends hide amounts. Carrier weight passes for active dose. Ingredient studies get quoted as if they were product studies.
Open Origin is building one formula the other way around: two actives, each printed by amount, each lot tested and the results published, and the research explained with its limits attached. Start with the ingredients, then read how we work.
Why Open OriginThe two actives
Two ingredients.
Nothing else.
Tributyrin carries butyrate, the short-chain fatty acid the cells lining the colon run on. Zinc L-carnosine is the complement, studied for how the gut lining holds up under challenge.
Zinc L-carnosine
The mucosal complement
In plain language
Zinc bound to L-carnosine, a dipeptide made from beta-alanine and L-histidine, in one ingredient complex.
PepZinGI® is the branded zinc L-carnosine selected for development.
Zinc L-carnosine, explainedSimplified ingredient diagrams. Illustrations are not molecular models.
Why these two
Formula 01
One formula, in the open.
CoreBiome® + PepZinGI®
The two actives are chosen. Manufacturer qualification and bench prototypes are under way. The final amounts, capsule format, and complete label get published together, with the first lot’s test results, before a single jar ships.
Where development standsWhat comes with the jar.
- 01
Every active printed by amount
No proprietary blends. The label states the amount of each active, and for tributyrin that means the net active amount, not the weight of the carrier it arrives in.
- 02
Every lot tested, results public
Each released lot gets finished-product testing for identity, amount, contaminants, and odor, and the certificate is published on this site under the lot number printed on the jar.
- 03
Evidence kept in context
Research on an ingredient is not research on this formula. We label which is which, cite the study, and say what it did not measure.
For life beyond the label
Less decoding.
More understanding.
A short explanation when you want the essentials. The full study when you want to check our reading of it. A real reply when there’s something else you’d like to ask.
How we work
Read the label before it exists.
The full label and lot results go to the launch list first.
Understand the ingredient forms.
Tributyrin and zinc L-carnosine, explained in plain language.
The launch list
Hear about it when it’s real.
Formula 01 is targeting late 2026. Leave your email and you’ll get three messages: the final label, the first lot’s test results, and the launch date.
Open to a conversation
Let’s talk.
Questions about an ingredient, the company, or what comes next? Supplier or business inquiry? Our inbox is open.
hello@openorigin.co